Vancomycin EP Impurity K Ditrifluoroacetate CAS 99759-13-4(Free Base)
| CAS No. | 99759-13-4(Free Base) |
| Molecular Formula | C67H77Cl2N9O24 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Vancomycin EP Impurity K Ditrifluoroacetate (C67H77Cl2N9O24C2HF3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Vancomycin EP Impurity K Ditrifluoroacetate (CAS 99759-13-4(Free Base)), a pharmacopoeial impurity reference standard (molecular formula C67H77Cl2N9O24C2HF3O2, MW 1577.31 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Vancomycin EP Impurity K Ditrifluoroacetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C67H77Cl2N9O24 2*C2HF3O2 |
| Molecular Weight | 1577.31 g/mol |
| Purity | >75% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 33.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 9 |
Related Vancomycin Standards
- Vancomycin EP Impurity D (CAS 101485-50-1)
- Vancomycin Hexapeptide (CAS 115236-65-2)
- 126985-51-1 MM 47761 Vancomycin, 22-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-D-arabino-hexopyranosyl)-2'-O-de(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-19-dechloro-2'-O-(6-deoxy-alpha-D-talopyranosyl)- MM-47761 (CAS 126985-51-1)
- Vancomycin (CAS 1404-90-6)
- Vancomycin Hydrochloride (CAS 1404-93-9)
- Vancomycin EP Impurity A HCl (CAS 213997-73-0)
- Vancomycin EP Impurity F (CAS 2415254-43-0)
- Vancomycin EP Impurity J (CAS 2416251-24-4)
Recommended Standards
- Vitamin B6 (Pyridoxine) Impurity 41 (CAS 53580-89-5（free base）)
- Tiotropium Bromide EP Impurity I (CAS 136521-48-7)
- Roxadustat Impurity N8 (CAS 808116-62-3)
- Methyl 3-iodo-6-methoxy-1H-indole-2-carboxylate (CAS 1708168-17-5)
- Tert-butyl 4-(2-aminophenyl)-3,6-dihydropyridine-1(2H)-carboxylate (CAS 955397-70-3)
- Methyl 5-bromo-2,3-dihydro-1h-indole-6-carboxylate (CAS 1788041-64-4)
- 3-Fluoropropyl (2,2,3,3,4,4,4-heptafluorobutyl) carbonate (CAS 1980048-54-1)
- Methyl Sinapate (CAS 20733-94-2)
- H-DL-Val-OH (CAS 516-06-3)
- Semaglutide impurity 51 (CAS CATO-C4X-222651)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com